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SUMMARY:Prof. Khaled A. Selim\, Heinrich Heine University Düsseldorf: Bei
 ng lazy is not always bad: Cyclic di-AMP signaling in cyanobacteria
DTSTART;TZID=Europe/Berlin:20251021T090000
DTEND;TZID=Europe/Berlin:20251021T100000
DTSTAMP:20260614T065401Z
UID:c11b55185a4f44489296a0fe80dcc320@www2.hrz.uni-marburg.de
CATEGORIES:()
CREATED:20241205T125047Z
DESCRIPTION:https://www2.hrz.uni-marburg.de/en/synmikro/grk2937/whats-on/d
 ates-and-events/grk2937_speaker-series_khaled-selim\nSpeaker Series. Abstr
 act: Because of their photosynthesis-dependent lifestyle\, cyanobacteria e
 volved sophisticated regulatory mechanisms to adapt to oscillating day-nig
 ht metabolic changes. How they coordinate the metabolic switch between aut
 otrophic and glycogen-catabolic metabolism in light and darkness is poorly
  understood. Recently\, we discovered that the second messenger c-di-AMP i
 s implicated in diurnal regulation. The carbon-sensor protein SbtB was ide
 ntified as a major c-di-AMP receptor. Adding to its cellular functions cat
 alog\, for first time\, we show also that c-di-AMP influences on nitrogen 
 metabolism\, implying new cellular roles for c-di-AMP. Additionally\, we f
 ound that the cyanobacterial pilus biogenesis and natural competence are r
 egulated by c-di-AMP/c-di-GMP and showed that the ComFB signaling protein 
 is a novel c-di-NMP-receptor protein\, widespread in bacterial phyla\, and
  required for DNA uptake.
LAST-MODIFIED:20251006T104633Z
LOCATION:SYNMIKRO Lecture Hall
URL:https://www2.hrz.uni-marburg.de/en/synmikro/grk2937/whats-on/dates-and
 -events/grk2937_speaker-series_khaled-selim
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